Poloxamer CAS 9003-11-6

Poloxamer CAS 9003-11-6

High-purity Poloxamer CAS 9003-11-6 for pharmaceuticals cosmetics and food industries with USP NF compliance and fast global shipping from Blissam

  • ✔ Throughput 10,000 Tons/Year
  • ✔ ISO 9001 Certified Quality Assurance
  • ✔ 5-Year Product Performance Guarantee
  • ✔ Lifetime Technical Support & Consultation
  • ✔ Comprehensive Safety Data Sheets
  • ✔ Online Quality Inspection Videos
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Introduction to Poloxamer

Poloxamer CAS 9003-11-6 is a highly versatile block copolymer widely used across various industries, prized for its unique chemical structure and functional properties. As a polyethylene-polypropylene glycol block copolymer, Poloxamer combines hydrophilic and hydrophobic segments, enabling it to act as an effective surfactant, emulsifier, and solubilizer. This flexibility makes it invaluable in pharmaceuticals, cosmetics, food, and research applications.

The CAS number 9003-11-6 is critical for accurate identification and quality assurance, ensuring the product meets rigorous standards and matches exact specifications. This precise classification helps manufacturers, researchers, and formulators to source the exact Poloxamer grade they need without confusion.

At Blissam, we pride ourselves on being a leading manufacturer and reliable supplier of Poloxamer CAS 9003-11-6. We focus on delivering high-purity, compliant products supported by robust quality control and regulatory compliance. Whether you need Poloxamer for sensitive pharmaceutical formulations or cosmetic production, Blissam offers tailored solutions backed by excellent service and global shipping options.

Choose Blissam for trusted quality, consistent supply, and expert support when you buy Poloxamer in the United States market.

What is Poloxamer CAS 9003-11-6

Poloxamer block copolymer properties

Poloxamer CAS 9003-11-6 is a polyethylene-polypropylene glycol block copolymer, widely recognized for its unique structure and versatile properties. It’s made up of hydrophilic polyethylene oxide (PEO) blocks and hydrophobic polypropylene oxide (PPO) blocks arranged in a triblock configuration (PEO-PPO-PEO). This structure allows Poloxamer to behave as both a surfactant and a stabilizer in various applications.

Common Types and Synonyms

Two popular variants of Poloxamer under CAS 9003-11-6 are:

  • Poloxamer 188 (also known as Pluronic F68)
  • Poloxamer 407 (Pluronic F127)

These grades differ in molecular weight and the ratio of polyethylene oxide to polypropylene oxide, which influences their physical properties and suitability for specific uses.

Key Properties of Poloxamer

  • Non-toxic and Biocompatible: Poloxamers are safe for pharmaceutical and cosmetic applications thanks to their excellent compatibility with biological systems.
  • Thermosensitive Behavior: They exhibit temperature-dependent sol-gel transitions—forming gels at body temperature while remaining liquid at lower temperatures, making them ideal for controlled drug delivery.
  • Amphiphilic Nature: Helps in solubilizing hydrophobic compounds, improving formulation stability.
  • Water-Soluble: Good solubility in water enhances its use as an emulsifier and surfactant.

These properties make Poloxamer CAS 9003-11-6 a valuable ingredient across pharmaceutical formulations, cosmetics, food products, and research applications needing safe and effective block copolymers.

Applications of Poloxamer

Poloxamer CAS 9003-11-6 is a highly versatile block copolymer widely used across multiple industries due to its unique properties as a solubilizer, stabilizer, and emulsifier. Here’s a detailed look at its key applications:

Pharmaceuticals

In the pharmaceutical sector, Poloxamer plays a critical role as a drug delivery system component. Its ability to enhance the solubility of poorly water-soluble drugs helps improve bioavailability. Poloxamer also acts as a stabilizer in formulations, ensuring consistent release profiles and protecting active ingredients. Common uses include:

  • Solubilizer for hydrophobic drugs
  • Stabilizer in injectable formulations and topical creams
  • Controlled release in gels and ointments

Cosmetics

Poloxamer is popular in cosmetics for its effectiveness as a surfactant, helping to form clear and stable emulsions. It enhances the texture and feel of various products such as:

  • Facial cleansers and makeup removers
  • Emulsion-based lotions and creams
  • Gentle foaming agents in shampoos and body washes

Food Industry

In food applications, Poloxamer CAS 9003-11-6 works as an emulsifier and texture enhancer. It helps improve the stability and consistency of products like baked goods, dairy items, and dressings by:

  • Improving emulsification to prevent ingredient separation
  • Enhancing mouthfeel and texture
  • Acting as a stabilizing agent in frozen desserts and sauces

Research and Biomaterial Development

In lab research, Poloxamer is valuable for developing biomaterials and cell-based models. Its thermosensitive properties make it ideal for use as:

  • A cell membrane mimetic in biophysical studies
  • A scaffold material in tissue engineering
  • A component in hydrogel formulations for controlled release and cell culture

By blending these qualities, Poloxamer CAS 9003-11-6 remains indispensable across sectors, meeting the precise needs of both commercial products and cutting-edge research.

Poloxamer Grades and Specifications

Poloxamer Grades Specifications Compliance

At Blissam, we offer a wide range of Poloxamer grades to fit various industrial and pharmaceutical needs. The most common grades include:

  • Poloxamer 124
  • Poloxamer 188
  • Poloxamer 338
  • Poloxamer 407

Each grade varies mainly in the balance between polyethylene glycol (PEG) and polypropylene glycol (PPG) blocks, which influences properties like molecular weight, viscosity, and solubility. These differences help tailor Poloxamer for specific uses such as drug delivery, cosmetics, or food applications.

Key Specifications

  • Molecular Weight

    Ranges from around 2,500 to 14,000 g/mol depending on the grade.

  • Viscosity

    Varies widely: Poloxamer 188 is more liquid-like, while Poloxamer 407 forms thicker gels.

  • Solubility

    All grades are water-soluble but show different behaviors in solution based on temperature and concentration.

Compliance and Quality Standards

Our Poloxamer products meet strict quality criteria and fully comply with international pharmacopeias and standards including:

  • USP (United States Pharmacopeia)
  • NF (National Formulary)
  • Ph. Eur (European Pharmacopoeia)
  • ChP (Chinese Pharmacopoeia)

This compliance ensures that our Poloxamer is reliable and safe for use in pharmaceuticals and food products.

Blissam’s High-Purity Customizable Poloxamer

We pride ourselves on delivering high-purity Poloxamer with options to customize grades to your exact needs. Whether you require specific molecular weight ranges or tailored viscosity profiles, we can meet those demands while maintaining consistent quality.

Blissam’s Poloxamer products come with detailed Certificates of Analysis (COA) and full technical support—ideal for customers who demand traceability and the highest standards.

Choosing Blissam means you get both the right Poloxamer grade and the confidence that it meets all your specification requirements.

Benefits of Choosing Blissam’s Poloxamer CAS 9003-11-6

When you choose Blissam’s Poloxamer, you’re getting more than just a product—you’re getting peace of mind and reliable performance tailored for the U.S. market. Here’s why Blissam stands out as your trusted Poloxamer supplier:

High-Quality Manufacturing

  • Produced under cGMP (current Good Manufacturing Practices) to ensure consistent purity and quality
  • Strict quality control means each batch meets USP, NF, and other pharmacopeia standards
  • Advanced facilities designed for handling sensitive raw materials like Poloxamer 188 and Poloxamer 407

Competitive Pricing and Bulk Supply

  • Flexible order sizes from small samples to large bulk shipments, perfect for pharmaceutical, cosmetic, or food applications
  • Transparent pricing designed to give you the best value without compromising quality
  • Customizable grades available to fit specific formulation needs

Certifications and Compliance

  • Certified to meet ISO standards along with USP, NF, and Ph Eur (European Pharmacopoeia) specifications
  • Material documentation, including Poloxamer SDS, is provided to support regulatory compliance and safe use
  • Committed to environmental and safety best practices for U.S. regulatory compliance

Fast and Reliable Global Shipping

  • Efficient logistics network ensuring timely delivery anywhere in the United States
  • Trusted packaging that preserves product integrity during transit
  • Flexible shipping options with tracking and customer notifications

Easy Access to Samples and Quotes

  • Quick turnaround on sample requests to help you evaluate Poloxamer grades before purchase
  • Responsive customer service ready to provide technical support and detailed product information
  • Simple online process to request bulk quotes or customized Poloxamer products

Choosing Blissam means you get a high-quality, compliant Poloxamer CAS 9003-11-6 product backed by a manufacturer experienced in meeting U.S. market demands. Contact us today to request your quote or sample and experience the difference tailored to your industry needs.

Safety and Regulatory Information for Poloxamer CAS 9003-11-6

Safety Profile and Toxicity

Poloxamer CAS 9003-11-6 is widely recognized for its non-toxic and non-irritant nature, making it a trusted ingredient across pharmaceuticals, cosmetics, and food industries. Extensive animal studies confirm its excellent biocompatibility and minimal risk of adverse reactions. This makes it suitable for sensitive applications such as drug delivery and topical formulations.

Material Safety Data Sheet Availability

For every batch of Poloxamer supplied by Blissam, the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) is readily available. These documents provide detailed information on:

  • Handling precautions
  • Health hazards
  • First-aid measures
  • Storage recommendations
  • Spill and disposal guidelines

Having easy access to the MSDS/SDS ensures safe usage and compliance with workplace safety protocols.

Regulatory Compliance and Standards

Blissam’s Poloxamer meets key regulatory requirements across major markets including the FDA (U.S. Food and Drug Administration), European Union (EU), and other global regulatory bodies. Our product complies with recognized pharmacopoeia standards such as:

  • USP (United States Pharmacopeia)
  • NF (National Formulary)
  • Ph. Eur (European Pharmacopoeia)
  • ChP (Chinese Pharmacopoeia)

This guarantees that the Poloxamer you receive is of consistent quality, purity, and safety, suitable for pharmaceutical, cosmetic, and food-grade applications.

Handling and Storage Guidelines

To maintain the high quality and safety profile of Poloxamer CAS 9003-11-6, follow these handling and storage practices:

  • Store in a cool, dry place away from direct sunlight and moisture
  • Use proper protective equipment (gloves, goggles) to avoid unnecessary contact
  • Keep containers tightly sealed when not in use
  • Avoid contamination by using clean tools and environments during processing
  • Follow all local regulations on chemical storage and disposal

By adhering to these guidelines, you ensure product stability and user safety throughout the supply chain and application processes.

Blissam is committed to providing safe, compliant, and reliable Poloxamer products supported by full documentation and expert guidance for your peace of mind.

How to Buy Poloxamer CAS 9003-11-6 from Blissam

Simple Ordering Process for Poloxamer

At Blissam, buying Poloxamer CAS 9003-11-6 is straightforward and designed to meet your exact needs:

  • Request an online quote easily through our website for transparent pricing.
  • Place bulk orders with flexible quantity options to fit your project or production scale.
  • Looking for something specific? We offer custom synthesis to tailor Poloxamer grades or properties for your application.

Reliable Shipping and Delivery

We understand timely delivery matters:

  • Global shipping ensures your Poloxamer reaches you no matter where you are in the United States or beyond.
  • If you prefer a quicker local option, we have authorized distributor partnerships in key U.S. regions.
  • Packaging is secure and compliant with all transportation standards for chemical products.

Expert Customer Support and Documentation

We back our product with dedicated support:

  • Technical assistance is available to help you choose the right Poloxamer grade and understand specifications.
  • Access to Certificate of Analysis (COA) and full Material Safety Data Sheet (MSDS)/SDS documentation upon request.
  • Reach out anytime for pricing, product details, or any questions related to Poloxamer in pharmaceuticals, cosmetics, or industrial uses.

Contact Blissam Today

For a quick quote or sample of Poloxamer CAS 9003-11-6, contact us directly via phone or email. Our team is here to ensure you get the quality and service you expect from a top Poloxamer supplier.

Frequently Asked Questions about Poloxamer CAS 9003-11-6

What is Poloxamer CAS 9003-11-6 used for

Poloxamer CAS 9003-11-6 is a versatile block copolymer widely used across industries. Its primary applications include:

  • Pharmaceuticals: Acts as a solubilizer and stabilizer in drug delivery systems, improving bioavailability.
  • Cosmetics: Serves as a surfactant in emulsions and cleansers, offering gentle skin compatibility.
  • Food Industry: Functions as an emulsifier and texture enhancer.
  • Research: Used in cell membrane mimetics and biomaterial development.

What grades of Poloxamer does Blissam offer

Blissam supplies a range of high-quality Poloxamer grades tailored to meet diverse needs, including:

  • Poloxamer 124
  • Poloxamer 188
  • Poloxamer 338
  • Poloxamer 407

Each grade comes with detailed specifications covering molecular weight, viscosity, and solubility, and is compliant with USP, NF, Ph Eur, and ChP standards. We also offer customizable grades designed to fit specific formulations and processes.

Is Poloxamer safe for pharmaceutical use

Yes, Poloxamer CAS 9003-11-6 is non-toxic, biocompatible, and widely recognized as safe for pharmaceutical applications. It meets regulatory standards from the FDA, EU, and other global bodies. Blissam provides comprehensive Safety Data Sheets (SDS) and documentation to support your regulatory and safety assessments.

How can I request a Poloxamer sample from Blissam

Requesting a Poloxamer sample is simple and straightforward:

  • Visit our website or contact our customer support directly.
  • Specify the grade and quantity you need.
  • We offer fast shipping across the United States to help you evaluate our product before placing bulk orders.
  • Technical support is available to assist with any questions related to product specs or application guidance.

For larger or custom orders, Blissam provides competitive pricing and flexible supply options tailored to your business needs.

Choosing Blissam as your Poloxamer supplier means reliable quality, regulatory compliance, and customer-focused service designed for the U.S. market.

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