Sodium Hydroxymethylglycinate CAS 70161-44-3

Sodium Hydroxymethylglycinate CAS 70161-44-3

Sodium Hydroxymethylglycinate is a widely used broad-spectrum antimicrobial preservative ideal for cosmetic and personal care applications. Known as a reliable formaldehyde-releasing agent, it provides effective preservation with low formaldehyde release, making it a safer alternative to traditional formaldehyde donors. This ingredient helps extend the shelf life of products by preventing microbial contamination while maintaining formulation stability.

Synonyms and Aliases:

• • Glycine sodium salt preservative
  • N-(Hydroxymethyl)glycine monosodium salt
  • Sodium hydroxymethylamino acetate
  • Sodium hydroxymethylglycinate preservative

Chemical Structure and Properties

• Molecular formula: C3H6NO3Na
• Molecular weight: 121.08 g/mol
  Sodium Hydroxymethylglycinate is essentially the sodium salt of N-(hydroxymethyl)glycine, featuring chemical properties that contribute to its excellent solubility in water and stability in typical cosmetic and pharmaceutical formulations.

Physical Appearance

The product typically appears as a white crystalline powder or an off-white aqueous solution, depending on the supplier and specific preparation. For ease of use, it dissolves readily in water, making it highly compatible with a variety of product bases including shampoos, lotions, creams, and other aqueous systems.

This balanced mix of chemical performance and practical usability makes Sodium Hydroxymethylglycinate a go-to preservative for many formulators in the United States, meeting both safety concerns and effectiveness in preserving personal care and industrial products.

As a Sodium Hydroxymethylglycinate supplier, it is critical to source material with verified identification to ensure product performance and regulatory compliance across markets such as the USA, EU, and China.

Key Features and Benefits of Sodium Hydroxymethylglycinate

Sodium Hydroxymethylglycinate stands out as a broad-spectrum antimicrobial preservative, making it an effective choice for preventing the growth of bacteria, yeast, and mold in various formulations. As a formaldehyde-releasing agent, it provides lasting preservation with low formaldehyde release, helping manufacturers meet safety standards while maintaining product integrity.

This preservative is highly suitable for cosmetic and personal care products, including shampoos, lotions, and creams, where maintaining formula stability and safety is crucial. Its water solubility ensures easy integration into aqueous solutions, while its chemical stability under typical formulation conditions guarantees consistent performance throughout the product’s shelf life.

Key benefits include:

• Effective protection against a wide range of microbes
• Controlled and minimal formaldehyde release for safer formulations
• Compatibility with a variety of cosmetic and personal care ingredients
• Stability in water-based systems without compromising preservative function

These qualities make Sodium Hydroxymethylglycinate a reliable choice for formulators looking for an efficient and user-friendly antimicrobial preservative that complies with regulatory and consumer demands.

Applications and Uses of Sodium Hydroxymethylglycinate

Sodium Hydroxymethylglycinate (CAS 70161-44-3) is a versatile preservative widely used across multiple industries due to its broad antimicrobial effectiveness and low formaldehyde release. Here’s a clear overview of where and how it’s commonly applied:

Cosmetics and Personal Care Products

• Shampoos, conditioners, and hair treatments: Keeps formulas fresh by preventing microbial growth without affecting product performance.
• Lotions and creams: Provides long-lasting preservation for water-based skin care items while maintaining skin compatibility.
• Makeup and other personal care items: Used to support product stability and safety in a variety of cosmetic formulations, ensuring a longer shelf life.

Pharmaceuticals and Topical Formulations

• Ideal for topical creams, gels, and ointments as a preservative that effectively prevents contamination while being gentle on skin.
• Used in formulations requiring microbial stability without compromising the product’s therapeutic benefits or user safety.

Industrial Applications

• Employed as a preservative in various aqueous solutions, such as cleaning products, textiles, and other water-based industrial formulations.
• Helps maintain product integrity and extends shelf life in environments where microbial contamination is a concern.

Key benefits of Sodium Hydroxymethylglycinate in applications:

• Acts as a low formaldehyde-releasing agent, suitable for consumers seeking safer preservative options.
• Highly water-soluble and stable, making it easy to incorporate into numerous formulations without altering their properties.
• Compatible with a broad range of ingredients typical in U.S. cosmetic and pharmaceutical markets.

By choosing Sodium Hydroxymethylglycinate as your preservative, you get a reliable solution trusted in both consumer care and industrial products, meeting the quality expectations here in the United States.

Technical Specifications of Sodium Hydroxymethylglycinate

Purity

Our Sodium Hydroxymethylglycinate meets a high purity standard of ≥ 99%, ensuring consistent performance as a reliable antimicrobial preservative in your formulations.

Appearance

This product is supplied as a white crystalline powder, easy to handle and incorporate into various product bases. Its uniform texture supports simple blending without clumping.

pH Range

When dissolved, Sodium Hydroxymethylglycinate typically has a pH between 8.5 and 9.5 (in a 1% aqueous solution), making it mildly alkaline but stable under most cosmetic and personal care conditions.

Solubility

Our preservative is fully water-soluble, which means it dissolves readily in water-based formulations like lotions, creams, shampoos, and topical pharmaceuticals. This improves ease of use and efficacy.

Storage Conditions

To maintain the preservative’s effectiveness:

• Store in a cool, dry place away from direct sunlight
• Keep the container tightly sealed to avoid moisture uptake
• Ideal storage temperature is between 15-25°C (59-77°F)

Shelf Life

When stored properly, Sodium Hydroxymethylglycinate offers a shelf life of 24 months, giving you ample time for inventory management without compromising quality or preservative action.

These technical specifications highlight why Sodium Hydroxymethylglycinate is a top choice for a stable, effective antimicrobial preservative suitable for the U.S. market, especially in cosmetic preservatives, formaldehyde releaser preservatives, and personal care products.

Regulatory Compliance and Safety of Sodium Hydroxymethylglycinate CAS 70161-44-3

Regulatory Status in Key Markets

Sodium Hydroxymethylglycinate is widely accepted as a preservative and formaldehyde-releasing agent in major regions including the United States, European Union, and China. In the USA, it is generally recognized as safe for use in cosmetic and personal care products under the conditions of use specified by the FDA. The EU Cosmetic Regulation (EC) No. 1223/2009 allows its use within defined concentration limits, ensuring consumer safety. Likewise, China’s National Medical Products Administration includes it in its list of permitted preservatives for personal care and pharmaceutical formulations.

Safety Profile and Handling Instructions

Sodium Hydroxymethylglycinate is considered low in toxicity when used at recommended levels. It slowly releases formaldehyde, which is why safety and exposure limits are strictly regulated. Always handle it with care to avoid inhalation, eye, or skin contact:

• Use personal protective equipment such as gloves and goggles.
• Work in well-ventilated areas.
• Avoid direct exposure to concentrated powder or solutions.

Toxicological Data

• Irritation: Mild skin and eye irritation can occur on direct exposure to concentrated material.
• Sensitization: Low potential for skin sensitization when formulated correctly.
• Toxicity: Non-mutagenic and non-carcinogenic at typical usage concentrations.
• Formaldehyde release is minimal but monitored to stay below safety thresholds set by regulatory bodies.

Recommended Usage Levels and Restrictions

• Generally limited to 0.1% to 0.5% concentration in finished cosmetic products.
• Maximum permissible levels vary by region; always consult local regulations.
• Not recommended for leave-on products without confirming compliance, especially in markets with strict formaldehyde releaser guidelines.
• Avoid combining with strong acids or oxidizing agents as this can degrade product stability and increase formaldehyde release.

Sodium Hydroxymethylglycinate is a reliable antimicrobial preservative with well-established regulatory acceptance. Proper handling, adherence to local guidelines, and recommended usage levels ensure safe application in cosmetics, personal care, and pharmaceutical products in the United States and globally.

Sodium Hydroxymethylglycinate Packaging and Supply Details

Available Packaging Sizes

We offer Sodium Hydroxymethylglycinate CAS 70161-44-3 in multiple packaging options suitable for different needs:

• 5 kg bags for small-scale use or lab testing
• 25 kg drums for medium batch production
• 1000 kg IBC totes for large industrial orders

This variety ensures you get the right package size whether you’re a small cosmetics formulator or a large manufacturer.

Storage and Transport Guidelines

To maintain the quality and stability of Sodium Hydroxymethylglycinate:

• Store in a cool, dry place away from direct sunlight and moisture.
• Keep containers tightly sealed when not in use to avoid contamination or moisture absorption.
• Transport under standard conditions, avoiding extreme heat or freezing temperatures to preserve product integrity.

Following these storage and transport practices helps keep the preservative effective and ready for use in your cosmetic, pharmaceutical, or industrial formulations.

Supply Capacity and Lead Times

We maintain a consistent supply capacity to meet the demands of manufacturers and formulators across the USA.

• Typical lead times range from 1 to 3 weeks, depending on order size and shipping location.
• We work closely with our logistics partners to ensure timely delivery and reliable supply chain management.
• Custom batch sizes or contract manufacturing can be arranged for larger or specialized orders.

Choosing us as your Sodium Hydroxymethylglycinate supplier means you can count on steady stock, fair pricing, and prompt service tailored to your production schedule.

Why Choose Blissam for Sodium Hydroxymethylglycinate

When it comes to sourcing Sodium Hydroxymethylglycinate CAS 70161-44-3, Blissam stands out as a trusted Sodium Hydroxymethylglycinate supplier in the U.S. market. Here’s why choosing us benefits your formulation and business:

Quality Assurance and Manufacturing Standards

At Blissam, quality is non-negotiable. We follow strict manufacturing protocols and comply with international quality standards to ensure every batch of sodium hydroxymethylglycinate meets or exceeds purity and performance expectations. Our advanced quality control systems verify chemical properties and stability, making sure the antimicrobial preservative you receive is reliable and consistent.

Custom Manufacturing Capabilities

Understanding that different cosmetic, pharmaceutical, and industrial applications require unique specifications, Blissam offers custom manufacturing and tailored solutions. Whether you need specific purity levels, particle size, or packaging options, our flexible production facilities accommodate your needs. This gives you an edge in formulating with a preservative that fits perfectly within your product parameters.

Technical Support and Documentation Availability

We know that seamless integration of formaldehyde releaser preservatives like sodium hydroxymethylglycinate requires detailed knowledge. Our team provides comprehensive technical support and easy access to essential documents such as technical data sheets, safety datasheets, and regulatory compliance certificates. This support helps you navigate formulation challenges and regulatory requirements confidently.

Competitive Pricing and Reliable Supply Chain

Blissam combines quality with cost-efficiency. Our competitive pricing structure aligns with your budget without compromising product integrity. Plus, with our dependable supply chain and robust inventory, we ensure consistent availability and timely delivery of sodium hydroxymethylglycinate, preventing downtime in your production.

Choosing Blissam as your sodium hydroxymethylglycinate manufacturer means partnering with a supplier who prioritizes quality, customization, support, and value—helping you succeed in the competitive cosmetic preservative market.

Explore our other specialty surfactants and preservatives like Sodium Dodecylbenzenesulphonate CAS 25155-30-0 to complete your formulation needs.

FAQ Sodium Hydroxymethylglycinate Usage Compatibility and Safety

Is Sodium Hydroxymethylglycinate safe for use in cosmetics and personal care products?

Yes, Sodium Hydroxymethylglycinate is widely recognized as a safe broad-spectrum antimicrobial preservative when used within recommended limits. It acts as a low formaldehyde releaser, releasing minimal formaldehyde, which helps maintain product safety and stability without significant health risks. Regulatory bodies in the US, EU, and other markets approve its use within specified concentrations.

What is the typical usage level for Sodium Hydroxymethylglycinate in formulations?

The recommended usage levels range from 0.1% to 0.5% depending on the product type and preservation needs. Staying within this range ensures effective antimicrobial action without impacting product quality or consumer safety.

Can Sodium Hydroxymethylglycinate be used in all types of cosmetic formulations?

Yes, it is compatible with a wide variety of cosmetics and personal care products, including shampoos, lotions, creams, and topical pharmaceuticals. Its water solubility and stability make it easy to incorporate in multiple formulation types as a preservative.

Does Sodium Hydroxymethylglycinate release formaldehyde?

It is a formaldehyde-releasing preservative, but the amount of formaldehyde released is very low and controlled. This design allows it to provide antimicrobial protection while minimizing formaldehyde exposure, making it suitable for sensitive formulations where formaldehyde levels must be kept minimal.

Are there any known irritations or sensitivities associated with Sodium Hydroxymethylglycinate?

Generally, it is well-tolerated in cosmetic and pharmaceutical applications. As with any preservative, some individuals with highly sensitive skin may experience irritation. It’s advised to conduct patch tests during product development to ensure compatibility with your target consumer base.

How should Sodium Hydroxymethylglycinate be stored?

Store in a cool, dry place, away from direct sunlight and extreme temperatures to maintain its effectiveness and shelf life. Follow storage guidelines specified in the technical data sheet for best results.

Is Sodium Hydroxymethylglycinate approved by regulatory agencies?

Yes, it complies with cosmetic regulations in major markets such as the United States (FDA), European Union (Cosmetics Regulation), and China (CFDA) with established safety profiles and permitted usage limits.

Can Sodium Hydroxymethylglycinate be combined with other preservatives?

Yes, it is often combined with other preservatives to enhance the antimicrobial spectrum and improve overall product stability. Compatibility depends on the specific formulation, so testing is essential to optimize preservative blends.

For any additional questions or specific formulation advice on Sodium Hydroxymethylglycinate CAS 70161-44-3, contact our technical support team. We’re here to help you get the most out of this effective, reliable preservative.