Product Overview LY 171883 Thromboxane Antagonist CAS 88107-10-2
LY 171883 is a selective thromboxane A2 (TXA2) receptor antagonist widely used in pharmaceutical and cardiovascular research. As a potent TXA2 receptor inhibitor, it functions by blocking thromboxane-mediated platelet aggregation and vasoconstriction, making it a critical compound for investigating mechanisms of platelet function and cardiovascular disease.
This research chemical, identified by CAS number 88107-10-2, plays a significant role in studying platelet aggregation inhibition and vascular smooth muscle responses. Its targeted action on the TXA2 receptor renders it valuable in cardiovascular pharmacology, particularly in exploring therapeutic interventions for thrombotic disorders, hypertension, and other platelet-related pathologies.
Researchers leverage LY 171883 to elucidate thromboxane receptor signaling pathways and to evaluate novel antiplatelet and vasodilator drug candidates. Its specificity and efficacy in vitro and in vivo provide a reliable tool for advancing cardiovascular drug development and understanding platelet physiology at the molecular level.
Key Highlights
- Selective TXA2 receptor antagonist with potent inhibitory activity
- Essential for cardiovascular research and antiplatelet drug development
- Facilitates the study of platelet aggregation and thromboxane receptor pathways
- Widely used in pharmaceutical and biomedical research on thrombotic diseases
LY 171883 is thus a crucial reagent for scientists focused on cardiovascular disease mechanisms, enabling precise modulation of thromboxane-mediated effects.
Product Identification LY 171883 CAS 88107-10-2
Chemical Name
- LY 171883
CAS Number
- 88107-10-2
Molecular Formula
- C₂₂H₂₄N₂O₃
Molecular Weight
- 368.43 g/mol
Chemical Structure
- LY 171883 is structurally characterized by a selective thromboxane A2 (TXA2) receptor antagonist framework. Its chemical structure includes key functional groups responsible for its binding affinity and inhibitory action on TXA2 receptors.
- Note: For detailed structural analysis or visuals, refer to supplier-provided chemical structure images or databases.
This identification information ensures you’re getting a precise, research-grade TXA2 receptor inhibitor that supports your work in cardiovascular and platelet aggregation studies. As a trusted LY 171883 chemical supplier, we offer this product with guaranteed consistency and purity to help propel your research and development efforts.
Physicochemical Properties of LY 171883 Thromboxane Antagonist
Appearance and Purity Level
LY 171883 is typically supplied as a white to off-white crystalline powder, ensuring ease of handling in research settings. The product maintains a high purity level of ≥ 98%, verified through rigorous quality control protocols, which is essential for reliable results in cardiovascular and platelet aggregation studies.
Melting Point and Solubility
The compound exhibits a melting point range of approximately 210–214°C, reflecting its solid crystalline nature. LY 171883 is moderately soluble in organic solvents like DMSO and ethanol, which makes it suitable for various in vitro assays. Its solubility in aqueous solutions is limited, so appropriate solvents or co-solvents are recommended for experimental setups.
Stability and Storage Conditions
LY 171883 demonstrates good chemical stability when stored under recommended conditions. It should be kept in a cool, dry place away from direct sunlight and moisture. For prolonged shelf life, storage at 2-8°C in tightly sealed containers is advised to prevent degradation. Proper handling ensures consistent activity as a TXA2 receptor antagonist in cardiovascular pharmacology research.
For more detailed chemical profiles, you can refer to our product specifications or contact our technical support team.
Applications and Usage of LY 171883 Thromboxane Antagonist
LY 171883 (CAS 88107-10-2) is widely used in cardiovascular pharmacology research due to its role as a potent thromboxane A2 (TXA2) receptor antagonist. It effectively inhibits platelet aggregation, making it an essential tool for studies focusing on thromboxane receptor signaling and antiplatelet drug development.
Key Research Areas
- Cardiovascular disease studies: LY 171883 helps explore mechanisms involved in blood clot formation and vascular function.
- Thromboxane receptor investigations: It provides selective inhibition of TXA2 receptors, supporting detailed receptor binding and function studies.
- Platelet aggregation research: Used to assess the impact of thromboxane signaling on platelet activation and aggregation in various models.
Experimental Applications
- Suitable for both in vitro assays, such as cell culture and receptor binding studies.
- Effective in in vivo models for evaluating pharmacodynamic effects related to thrombosis and vascular responses.
Pharmaceutical and Chemical Industry Use
Beyond academic research, LY 171883 serves as a valuable pharmaceutical intermediate and reference standard in the development of new antithrombotic and cardiovascular agents. Its high purity and consistent performance make it well-suited for use in drug discovery pipelines and biochemical assays.
LY 171883 is ideal for researchers and industry professionals working on thromboxane-related targets, cardiovascular disease mechanisms, and novel antiplatelet therapies.
Packaging and Supply of LY 171883 CAS 88107-10-2
Available Quantities for LY 171883
We offer LY 171883 in multiple quantities to fit different research and industrial needs, including:
- Milligram (mg) scale for small batch experiments
- Gram (g) quantities for moderate usage and scale-up
- Kilogram (kg) quantities for large-scale pharmaceutical or chemical production
This flexibility makes it easy to source the right amount whether you are conducting initial lab tests or larger preclinical studies.
Packaging Details
LY 171883 is supplied in sealed, airtight bottles to preserve its stability and purity. Packaging options include:
- Small sample packs suitable for first-time users or trial runs
- Larger bottles designed for ongoing research or production use
Each package is clearly labeled with product information including CAS number 88107-10-2 and batch details to ensure traceability and compliance with your lab standards.
Storage and Shelf Life
To maintain the integrity of LY 171883, follow these storage guidelines:
- Store the product in a cool, dry place, away from direct sunlight
- Keep containers tightly sealed when not in use to prevent moisture and contamination
- Typical shelf life is 12 to 24 months when stored under recommended conditions
Proper storage helps ensure you receive consistent, high-purity thromboxane receptor antagonist material for your cardiovascular and platelet aggregation research.
By offering secure packaging and reliable supply options, we support your work with LY 171883 across all phases of pharmaceutical and chemical development.
Quality Assurance for LY 171883 TXA2 Receptor Antagonist
At Blissam, quality assurance is a top priority for LY 171883 (CAS 88107-10-2), ensuring you receive a reliable thromboxane antagonist for your research and development projects. Our product complies with ISO and GMP standards wherever applicable, underscoring our commitment to consistent quality.
Analytical Data and Purity Verification
We provide comprehensive analytical data to support the high purity and identity of LY 171883, including:
- HPLC (High-Performance Liquid Chromatography): Confirms purity ≥ 98%, ensuring minimal impurities for accurate cardiovascular and platelet aggregation studies.
- NMR (Nuclear Magnetic Resonance) Spectroscopy: Verifies structural integrity and chemical consistency for every batch.
- MS (Mass Spectrometry): Confirms molecular weight and composition, protecting against batch variability.
Batch to Batch Consistency
We understand how crucial consistent supply quality is for your experiments and pharmaceutical applications. Our strict quality control protocols guarantee:
- Uniform purity and potency across all batches of LY 171883.
- Reliable performance in both in vitro and in vivo cardiovascular research.
- Transparent batch documentation for traceability and compliance.
Choose Blissam for LY 171883 with confidence—our quality assurance practices ensure you get the same high-standard thromboxane A2 receptor antagonist every time.
Safety and Handling of LY 171883 Thromboxane Antagonist
Hazards and Safety Precautions
When working with LY 171883 (CAS 88107-10-2), it’s important to follow standard laboratory safety practices. This compound is primarily used as a TXA2 receptor antagonist in research, so handling it with care is essential to avoid exposure risks.
- Avoid inhalation, ingestion, and skin contact. Use personal protective equipment such as gloves, lab coat, and safety glasses.
- Work in a well-ventilated area or a chemical fume hood to minimize inhalation hazards.
- In case of accidental contact with skin or eyes, rinse immediately with plenty of water and seek medical advice if irritation persists.
MSDS Information Overview
The Material Safety Data Sheet (MSDS) for LY 171883 covers all critical safety data, including:
- Physical and chemical hazards
- Recommended personal protective equipment
- First aid measures
- Firefighting techniques
- Accidental release response
- Disposal considerations
Always review the MSDS before handling the compound to understand its potential hazards and emergency procedures.
Proper Storage and Disposal Guidelines
- Store LY 171883 in a cool, dry place, preferably at low temperatures (2–8°C) and protected from light to maintain its stability and purity.
- Keep the container tightly sealed to avoid contamination and moisture exposure.
- Dispose of all unused chemical and waste material following local, state, and federal regulations for hazardous chemical waste.
- Avoid environmental release; do not pour into drains or sewers.
Adhering to these safety and handling recommendations ensures safe use and long-term quality of LY 171883 for your pharmaceutical and cardiovascular research applications.
Ordering Information for LY 171883 CAS 88107-10-2
Pricing and Quote Requests
We offer competitive pricing on LY 171883, a high-purity thromboxane A2 receptor antagonist ideal for cardiovascular and platelet aggregation research. For exact pricing, please contact us directly for a personalized quote based on your quantity needs and delivery location.
Lead Time and Shipping
Our standard lead time ranges from 3 to 7 business days, depending on stock availability and order size. We ship across the United States with reliable carriers, ensuring timely and secure delivery. Expedited shipping options are available for urgent research projects.
Custom Synthesis and Bulk Supply
- Custom synthesis services are available if your research requires tailored modifications or specific formulations of LY 171883.
- We support bulk orders starting from grams up to kilograms, perfect for pharmaceutical research labs and industrial applications.
- All batches come with consistent quality and certification, maintaining the purity and integrity researchers expect from a trusted supplier.
For all ordering inquiries or special requests related to LY 171883 CAS 88107-10-2, reach out to our sales team. We’re here to provide solutions that match your research needs and help you secure the materials you require with ease.
About Blissam Supplier of LY 171883 and Research Chemicals
Blissam is a trusted manufacturer and supplier specializing in high-quality research chemicals, including LY 171883 (CAS 88107-10-2). With years of experience serving the U.S. pharmaceutical and chemical industries, we provide reliable sources for compounds like this TXA2 receptor antagonist used widely in cardiovascular and platelet aggregation studies.
Credibility and Manufacturing Standards
- Strict quality control following ISO and GMP guidelines ensures we deliver LY 171883 with consistent purity, typically ≥98%, meeting research-grade standards.
- Our production facilities use state-of-the-art equipment and analytical methods like HPLC, NMR, and MS to guarantee batch-to-batch consistency.
- We pride ourselves on transparent documentation and compliance, so you know exactly what you’re getting with every order.
Commitment to Quality and Customer Support
- We put customer needs first by offering technical support from knowledgeable chemists who understand the applications of LY 171883 in cardiovascular pharmacology and antiplatelet drug development.
- Whether you’re conducting in vitro or in vivo research, our team helps you choose the right product form and packaging size suited to your study.
- Prompt response times and tailored solutions reflect our commitment to making your research process smooth and efficient.
Easy Access to Technical Support
- For questions about LY 171883’s properties, uses, or handling, you can quickly reach our experienced technical team via phone or email.
- We provide detailed Material Safety Data Sheets (MSDS) and handling instructions to ensure safe and compliant use of all chemicals, including thromboxane receptor inhibitors.
- Our support doesn’t stop at purchase—we help with custom synthesis, bulk orders, and logistics for a seamless experience.
By choosing Blissam for your LY 171883 supply, you’re partnering with a reliable American chemical supplier that understands the needs of cardiovascular research and the pharmaceutical industry.
Related Products Alternatives for LY 171883 Thromboxane Receptor Antagonist
At Blissam, we offer a selection of thromboxane receptor antagonists and related compounds to support your cardiovascular and platelet aggregation research. If you’re working with LY 171883 (CAS 88107-10-2) and need alternatives or similar agents, our catalog has several options designed for precision and reliability in TXA2 receptor inhibition studies.
Other Thromboxane Receptor Antagonists
- SQ 29,548 – A well-known TXA2 receptor inhibitor widely used in cardiovascular and platelet function research.
- Ifetroban – A selective thromboxane A2 receptor antagonist with strong applications in thrombosis and hypertension studies.
- S-1452 – Another effective TXA2 antagonist with research use in vascular and platelet aggregation models.
Each of these compounds offers unique properties and potency, allowing you to tailor your experiments or pharmaceutical development projects based on specific requirements.
Similar Compounds and Analogs Supplied by Blissam
- LY 319798 – An analog to LY 171883 used for extended studies in thromboxane receptor-related pathways.
- Thromboxane A2 receptor inhibitors with varied chemical backbones – Available for comparative screening and structure-activity relationship (SAR) research.
- Custom analog synthesis is available to meet specialized project needs that require structural or functional modifications.
Why Choose Blissam for Your Research Chemicals
- High purity (≥ 98%) and consistent batch quality across all thromboxane receptor antagonists.
- Comprehensive analytical data including HPLC, NMR, and MS to assure your research material integrity.
- Flexible supply options suited for both in vitro and in vivo studies.
- Expert support to help you select the best compound for your specific cardiovascular or platelet aggregation application.
If you are interested in bulk orders or need a custom analog of LY 171883, contact us to discuss tailored solutions that fit your research goals. Blissam stands ready to support your exploration of thromboxane receptor biology with reliable chemical reagents and alternatives.








